moa tirzepatide For the incretin crowd that has the of “all figured out” here is some new intriguing mouse and primate data from @Amgen with a GIPR antagonist-GLP1R agonist antibody #weightloss #obesity # Tirzepatide, a New Era of
Description
Non-Surgical : Offers an alternative to invasive weight-loss procedures

When someone's metabolism is already compromised, the dual GIP/GLP-1 mechanism provides more firepower to overcome that resistance

What GLP-1 Is in the Body GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in the gut in response to food

Interestingly, by combining GLP-1 and GIP agonism into a single molecule, the GIP/GLP-1 coagonist has enhanced therapeutic properties to improve glucose tolerance and induce weight loss, which was demonstrated in rodents, non-human primates and humans (Finan et al., 2013)

Staying on with the treatment over the long-term helps maintain these changes

Yes, based on my experience, it is