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[DOI] [PMC free article] [PubMed] [Google Scholar] 17.De Block C., Bailey C., Wysham C., Hemmingway A., Allen S.E., Peleshok J

We also see a lot of things that were not unexpected but interesting, she adds

This demonstrates that hormones secreted from the gastrointestinal tract during oral glucose administration are involved in promoting pancreatic insulin secretion

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For example, the FDAs approval of Lillys ZepBound (tirzepatide for chronic weight management) in late 2023 was based on phase III data showing superior weight loss compared to placebo

Ozempic targets only GLP-1, while Mounjaro targets GLP-1 and GIP