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CrossRef Lipidomic Analysis Reveals the Protection Mechanism of GLP-1 Analogue Dulaglutide on High-Fat Diet-Induced Chronic Kidney Disease in Mice Martin Ho Yin Yeung, Ka Long Leung, Lai Yuen Choi, Jung Sun Yoo, Susan Yung, Pui-Kin So, Chi-Ming Wong Frontiers in Pharmacology.2022;[Epub] CrossRef GLP-1 receptor agonists in diabetic kidney disease: current evidence and future directions Ji Hee Yu, So Young Park, Da Young Lee, Nan Hee Kim, Ji A Seo Kidney Research and Clinical Practice.2022

We observed that when we systemically administered liraglutide to the mice, it accumulated predominantly in the intestine rather than the brain, says co-corresponding author Bing Han, also of Southeast University

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At the same time, supply shortages and insurance constraints can influence dosing decisions

Recent meta-analyses of the major CVOTs for GLP-1RAs have also demonstrated an overall protective effect of GLP-1RAs on cardiovascular events [69, 70]