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The clinically most relevant and important action of DPP-4 inhibitors is the endogenous elevation of the incretin hormone concentration of GLP-1 that consecutively leads to a glucose-dependent stimulation of insulin secretion and an inhibition of glucagon secretion (10)

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Comparison of Single and Combined Treatment with Exenatide and Metformin on Menstrual Cyclicity in Overweight Women with Polycystic Ovary Syndrome

Overall, while GLP-1s enable some heavy obese patients to become eligible for orthopedic surgeries previously inaccessible due to high BMI, the predominant effect is a reduction in the need for such p...

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