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Glucose stimulates insulin release from pancreatic cells in a biphasic manner

VK2735 VK2735 is an advanced dual GIP/GLP-1 receptor agonist with promising efficacy and the potential to become a major competitor in the injectable obesity market

Synjardy is an oral diabetes medicine that combines empagliflozin with metformin in one tablet

GLP-1 medications have become a game-changer for weight loss and blood sugar control but theyre not meant to be used forever

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Participants received diet (500kcaldeficit per day) and exercise counseling during 2-week run-in, before being randomly assigned (with a telephone or web-based system) to once-daily subcutaneous liraglutide (1.2, 1.8, 2.4 or 3.0mg, n=9095), placebo (n=98) or open-label orlistat (120mg 3, n=95)