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When considering current recommendations from the ADA for add-on therapy to metformin in patients not achieving individualized glycemic goals, PIONEER 2 provides valuable data comparing the addition of either an oral GLP-1 receptor agonist or an SGLT-2 inhibitor

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Like other GLP-1 RAs, tirzepatides glucose-lowering is glucose-dependent, with low hypoglycemia risk unless combined with insulin or sulfonylureas

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Tirzepatide carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

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which glp-1 is serena williams taking on Why She Chose to Use Medication Serena Williams Opens Up About

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