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Key parameters include fasting glucose, HbA1c, liver enzymes (ALT, AST), lipid panel, and body composition metrics

Resources Clinicians and patients should educate themselves using reputable clinical resources and choose providers that prioritize informed consent and individualized care

A phase II RCT showed superior glycemic control and weight reduction in tirzepatide compared with dulaglutide (another GLP-1 agonist) or placebo, with good tolerability and acceptable safety profiles

Now, the thing about second-order effects is that the first-order has to play out to some critical degree

PLoS One 12 (5), e0177545

Adapted from Wadden et al