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Read article A plain-English summary of SURMOUNT-1: how effective tirzepatide was in obesity, who the study applied to, and what it still did not answer

Cholecystokinin secretion is suppressed by glucagon-like peptide-1: Clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs

Conclusion The findings of this systematic review and meta-analysis suggest that treatment with GLP-1 RAs may be associated with improvements across various intervals, including in papilledema and Visual Disturbances, which appear to be maintained for up to 24 months

Incretins are endogenous compounds, including GLP-1, that improve glycemic control once released into the circulation

Most people regain 510% of weight lost within the first 3 months after stopping, then stabilize if lifestyle habits remain consistent

Maybe the weight loss slowed to a crawl