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Any decision about using GLP-1 medications should be made in consultation with your doctor, especially if youre a new mother who is breastfeeding

Patients with pre-existing chronic kidney disease face compounded risk, as impaired renal function limits the body's ability to compensate for electrolyte shifts

The primary focus of current lawsuits against manufacturers of GLP-1 agonists is severe gastrointestinal side effects, including: Gastroparesis : Often referred to as stomach paralysis, this condition causes delayed stomach emptying and can lead to: Severe nausea and vomiting Abdominal pain and bloating Loss of appetite and weight loss Malnutrition and dehydration Difficulty eating and absorbing nutrients Ileus : Similar to gastroparesis but affecting the small intestine, ileus occurs when the intestinal muscles fail to move food properly through the digestive tract

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These differences can affect reconstitution

dNETs most frequently expressed the receptor (45% were positive), albeit typically at modest levels, while a smaller percentage of pNETs (13%) were GLP-1R positive, though typically strongly expressing when positive