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Description
Among the plethora of novel agents against diabetes, GLP-1RAs are known to exert various biological effects in extra-pancreatic tissues beyond controlling hyperglycemia (1)

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Even in diabetics without clinical gastroparesis, gastric emptying is slower in women than in men [25, 37]

Glucagon-like Peptide 1 Receptor Signaling in Acinar Cells Causes Growth-Dependent Release of Pancreatic Enzymes

These effects go beyond weight loss to address broader health risks

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