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Conclusions These data demonstrate for the first time the potent effect of semaglutide in reducing voluntary alcohol intake in non-human primates and further substantiate the need for clinical trials investigating the effect of semaglutide in patients with alcohol-use disorder.

Such improvements are crucial in mitigating the risk of obesity-related comorbidities, notably cardiovascular diseases and type 2 diabetes, which stand as leading contributors to global morbidity and mortality

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