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Originally developed to treat type 2 diabetes (T2D), these drugs have since delivered major advances in managing obesity and cardiovascular risk reduction

In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity

no major safety concerns were observed

It is equally about industrial policy, regulatory cooperation and long-term pharmaceutical resilience."At the regional level, the African Continental Free Trade Area (AfCFTA) provides an opportunity to strengthen regulatory cooperation and coordinate procurement strategies, ultimately increasing Africa's collective bargaining power."The COVID-19 lesson that risks being forgottenThe COVID-19 pandemic was widely expected to reshape the relationship between intellectual property and public health.In October 2020, South Africa and India proposed a temporary waiver of certain TRIPS obligations covering vaccines, diagnostics and treatments, arguing that existing intellectual property rules could become a barrier to equitable access during a global health emergency.The negotiations that followed demonstrated just how difficult it remains to reconcile commercial interests with public health priorities

Discover the facts about semaglutide and digestive symptoms, why dairy may cause discomfort, and how to manage gastrointestinal side effects effectively whilst taking this diabetes medication.

GLP-1s can negatively affect overall bone health, contributing to conditions like