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Documentation and governance When switching, pharmacists should make sure that the following actions are completed: Record the reason for switching (e.g

A 2-year carcinogenicity study was conducted with tirzepatide in male and female rats at doses of 0.15, 0.50, and 1.5 mg/kg (0.1-, 0.4-, and 1-fold the MRHD of 15 mg once weekly based on AUC) administered by subcutaneous injection twice weekly

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This allows the medication to disperse and prevents it from tracking back up through the needle path when you withdraw

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