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After receipt, standard refrigeration between 2 and 8 degrees Celsius is recommended for optimal stability

Some patients may experience more noticeable discomfort than others, reflecting individual variability in response to subcutaneous injections

Persistent severe symptoms such as unrelenting vomiting, dehydration, or severe abdominal pain require urgent medical assessment

The pH of compounded tirzepatide solutions also contributes to injection site discomfort

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Although the drugs are still pricey, the costs for some brands have dropped significantly since they were first introduced, says Wood