does glp-1 cause depression Doctors and patients across social media are reporting a kind of emotional flattening while on drugs. Anecdotally, physicians describe meaningful mental health gains — greater self-esteem, less shame over eating and The Antidepressant Effects of GLP-1
Description
Truncated glucagon-like peptide-1 (proglucagon 78-107 amide), an intestinal insulin-releasing peptide, has specific receptors on rat insulinoma cells (RIN 5AH) FEBS Letters

Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line
Amyloid-beta oligomers link depressive-like behavior and cognitive deficits in mice

If your strength is dropping like a rock and you feel softer, it might be time to tweak your training or calorie intake to preserve more muscle

Cost, Insurance Driving Move to Compounded Drugs Compounded GLP-1 medications are not approved by the FDA, and the agency issued a warning in June calling them potentially risky for patients. This hasnt stopped patients from switching to the unapproved drugs, and 35% of patients who took compounded GLP-1s left from a name brand drug, according to Gallup

The appointment follows FDA concerns over misleading marketing in some campaigns and regulatory scrutiny around telehealth companies prescribing GLP-1 therapies
