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This controlled and consistent drug delivery also helps reduce systemic side effects by eliminating peak concentrations on bolus (injection) administration
For a headache, acetaminophen or ibuprofen is useful

[DOI] [PubMed] [Google Scholar] 94.Kosiborod MN, et al

[DOI] [PubMed] [Google Scholar] 24.stergaard L., Frandsen C

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[DOI] [PubMed] [Google Scholar] 34.Morgan DE, Baron TH, Smith JK, Robbin ML, Kenney PJ
