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In human iPSC-derived dopaminergic neurons from PD patients with SNCA mutations, exendin-4 restored insulin signaling, improved mitochondrial function, and reduced -synuclein aggregation via PI3K/Akt/mTOR activation (26)

July 20, 2021

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Regulation of energy metabolism and mitochondrial function in skeletal muscle during lipid overfeeding in healthy men

Extended Dosing Horizons : By proving that cAMP levels can be pharmacologically sustained, this integrated protocol suggests that future GLP-1 treatments could be modified to last significantly longer, potentially reducing how frequently a patient must take the medication

Research from leading journals demonstrates that GLP-1 medications reduce inflammation through several pathways: 1