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GLP-1 receptor agonists have also been shown to cause weight loss in some individuals

Administration of GLP-1 or GLP-1RAs (including exenatide, geniposide, liraglutide, lixisenatide, and semaglutide) enhances neurogenesis in the dentate gyrus, hippocampus, olfactory bulb, and medial striatum in animal models, while modulating apoptotic pathways and increasing animal survival under extreme factors [24]
Whether the low endogenous concentration and the restricted pharmacokinetic action profile of endogenous GLP-1 metabolites are sufficient to elicit such effects under physiological circumstances remains questionable

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