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As with all retrospective cohort studies, alternative explanations for these findings are possible, although alternative explanations to account for these associations are not immediately apparent. Scratching the surface A KFF Health Tracking Poll released last fall indicated nearly one in five U.S

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This epidemic significantly increases the risk of various comorbidities, including type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), certain types of cancer, and kidney disease [3-6]

Orforglipron (LY3502970) is a non-peptide GLP-1R agonist currently in clinical development that has demonstrated promising effects on glycemic control and body weight reduction, highlighting the continued expansion of GLP-1-based therapeutic strategies [4]

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Incretin hormones in obesity and related cardiometabolic disorders: the clinical perspective