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[DOI] [PMC free article] [PubMed] [Google Scholar] [42].Chen L, Xu W, Zhang Y, Chen H, Han Y

Clinical renal outcomes exhibit notable uniformity across cardiovascular outcome studies

The implication is that there is a neuron population nucleus tractus solitarius GLP-1R neurons that can decrease appetite and cause weight loss without making individuals feel sick and so we hope that this finding will lead to the development of more selective weight loss drugs. We all know that nausea is almost always accompanied by appetite loss, and so we thought that the GLP-1 drugs may suppress appetite simply by making individuals feel nauseated

Simultaneously, GLP-1 suppresses glucagon secretion from pancreatic alpha cells, reducing hepatic glucose production when it is not needed