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Was very nice about having a nonpeptide agonist is its ability to be Co-formulated with other glucose lowering therapies, such as SGLT2 inhibitors and/or TZD for the management of diabetes and potentially cardiometabolic risk reduction.

Finally, we estimated HRs for non-melanoma skin cancer as a negative control outcome, assuming no causal relationship between use of GLP-1RAs or basal insulin and non-melanoma skin cancer

Br J Pharmacol 2018;175:242840

Patients with disc-at-risk anatomy or vascular risk factors should be counseled about NAION symptoms, while current data on AMD and retinal vein occlusion do not justify altering GLP-1 therapy

Generally, these effects are mild and short-lived, especially during the early stages of treatment