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Description
Proper Needle Angle and Insertion Depth Insert the needle at a 45-degree angle into the pinched skin fold of your upper arm, rather than perpendicular (90 degrees) insertion

JAMA, 325 (14), 1414

This was the first head-to-head comparison, published in the New England Journal of Medicine

Effects on Appetite and Digestion By lowering appetite and delaying gastric emptying, Wegovy can lead to smaller meals and less frequent eating

If you experience abdominal discomfort, changes in digestion, or worsening pancreatic symptoms after starting any GLP-1 therapy, report these changes promptly rather than waiting for a scheduled appointment

The trial tested different doses of orforglipron including 6mg, 12mg and 36mg against a placebo
