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Description
This first wave of GLP-1s were commercially successful (Victoza saw peak sales of ~$3.8B in 2018), but results were modest relative to todays market

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it is about the balance of minerals in your body

Side Effect: Constipation Causes: Insufficient fiber intake from fruits, vegetables, and whole grains can lead to constipation
This may indicate venous insufficiency that has gone untreated for a long time

Figure 12: Photograph Professor Vincent Marks (1930-2023), credit: Seaton)