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It is not recommended for those who are pregnant, planning to become pregnant, or breastfeeding

(2016) has shown that when patients receive GLP-1 therapy, there may be reduced activation in brain regions associated with reward processing and motivation when viewing high-calorie food images compared to baseline or placebo conditions

Mancini GBJ, Cheng AY, Connelly K, et al

TZP maintains a safety profile comparable to other GLP-1 receptor agonists, with common adverse effects being gastrointestinal
As the native GLP-1 has a short half-life, GLP-1 analogues have been produced to prolong effects and many of them could cross blood-brain barriers (BBB) such as Liraglutide (LG), lixisenatide, and exendin-4

Take phentermine exactly as directed and for the duration intended