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Comparing Long-Term GLP-1 Options to Avoid the Stop-and-Regain Cycle Wegovy is effective but expensive and sometimes subject to supply constraints

Additionally, it slows gastric emptying, keeping food in the stomach longer to increase fullness and reduce appetite

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Prior to this several other anti-obesity drugs had also proven disappointing due to adverse effects such as cardiovascular problems, increased suicidal risk and enhanced drug dependence and abuse (Mller, Blher, Tschp, DiMarchi)

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