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David has a BMI of 35 but no other diagnosed comorbidities yet

doi: 10.7759/cureus.25946, 12

For someone with obesity, the cardiovascular risk reduction from losing 25% of their body weight almost certainly exceeds the risk from a 5 to 10 beat per minute resting heart rate increase
2022;134(sup1):1827

Tolerability, pharmacokinetics and pharmacodynamics of the once-daily human GLP-1 analog liraglutide in Japanese healthy subjects: a randomized, double-blind, placebo-controlled dose-escalation study

R.RapaportM
