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Reviews of GLP-1R biology describe cyclic AMP and protein kinase A signaling as central components of receptor-linked cellular response patterns

Quantitatively, the LSc represents an area with some of the highest numbers of GLP-1Rs (12, 53), but here the GLP-1R expression is predominantly on neuronal projections, which could explain the lack of activation in this region

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Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis