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Clinical trials of GLP-1 medications have shown that while weight loss occurs, it includes both fat mass and some lean mass reduction, though the impact on respiratory muscle function specifically has not been well established

Penkowa M, Giralt M, Carrasco J, Hadberg H, Hidalgo J

GLP-1 programs that are provided by physicians via telehealth indicate the increasing need in medically-monitored weight-loss programs

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Another agent who came to us just ran into this exact scenario with a term case last month

Ultimately, this more than doubled weight loss demonstrates the potential benefit of early AOM intervention for those seeking solutions after unsatisfactory results with other approaches, including what many GLP-1 non-responder Reddit users frequently discuss