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GLP-1 receptor agonists act on the pancreas by enhancing insulin secretion, inhibiting glucagon release (see #4 below), and there is some evidence to suggest that they protect the beta cells from damage

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Ong Z.Y., Liu J.J., Pang Z.P., Grill H.J

The CDC currently recommends annual vaccination for people aged six months and older to prevent serious illness, hospitalisations, and death

On the other hand, Saxenda (liraglutide) requires a more hands-on approach, with a daily injection schedule

[DOI] [PubMed] [Google Scholar] 72.Schafer R., Schatz H

It activates the GLP-1 receptor, which in turn slows gastric emptying, inhibits the release of glucagon, and stimulates insulin production