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Why Did the FDA End Broad Compounding of Semaglutide and Tirzepatide

Starting in 2022, high demand led to shortages of semaglutide injections sold by Novo Nordisk under the brand names Ozempic and Wegovy, as well as tirzepatide injections Zepbound and Mounjaro from Eli Lilly

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Synonyms: LY3298176 Dual GIP/GLP-1 receptor agonist Tirz acetate (research form) Molar Mass: 4813.5 Da (may vary slightly depending on salt form) Storage Recommendations: Store lyophilized peptide between 36F and 46F (2C and 8C) in a dry, sealed container
The research on peptide stability consistently shows that physical agitation accelerates aggregate formation

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