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Semaglutide injection activates GLP-1 receptors throughout your digestive system, signaling fullness to your brain within hours of your first dose

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4.5.1 Post-discontinuation weight rebound and gestational risk Evidence for post-discontinuation weight rebound and related gestational risk is derived predominantly from non-PCOS or mixed-population cohorts rather than from PCOS-specific longitudinal studies

Semaglutide does activate GLP-1 receptors in brain regions that regulate mood and stress response, making direct causation plausible in some patients

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