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By March 20, 2025, Dhillon declared in a press release: "Skyes prime accomplishment in 2024 was the initiation and rapid advancement of its comprehensive Phase 2a clinical study of nimacimab

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When working with athletes or individuals with higher muscle mass, Rhodes also recommends indirect calorimetry testing so we can precisely measure their resting metabolic rate or RMR to better estimate how much nutrition their body needs once we multiply this by an activity factor. This tailored approach is important because often an athletes metabolism will be very different than what is calculated using our standardized equations, as these do not consider muscle mass or an individuals metabolic efficiency. Side effects can also be problematic, with some of the most common being gastrointestinal nausea, heartburn, and constipation

Checking blood sugar levels to avoid hypoglycemia (low blood sugar), which could cause dizziness or confusion

You also get access to personalized genetic insights through the optional Precision Peptide Genetic Test ($99 after month one), allowing your provider to tailor dosing and side effect strategies to your unique biology

They may suggest adjusting your dose schedule or exploring ways to ease the symptoms