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However, this phenomenon has also raised serious questions about safety, pregnancy outcomes, and the right medical approach for couples seeking to conceive

Arch Ophthalmol 1998;116:7:874-86

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Patients with T2D not adequately controlled on therapy with metformin and insulin glargine as baseline therapy received either tirzepatide at the doses used in the SURPASS trials or placebo during the 40-week study setting

Early gastroparesis symptoms: acid reflux, heartburn, nausea and vomiting, abdominal distension or bloating, early satiety (getting full after only a few bites) Early kidney dysfunction-proteinuria, swelling of extremities (hands and feet), increased fatigue, and weakness

[21] [2] Long-term success with these therapies requires ongoing treatment in most cases