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As addiction progresses, wanting increasingly dominates and becomes dissociated from liking.148 The dark side hypothesis of addiction suggests that impulsivity, compulsivity, and negative urgency emerge from stress experienced during withdrawal or the negative affective phase, potentially persisting months post-withdrawal

We're simplifying this a lot, of course

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The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

GolpichMAminiEHemmatiFIbrahimNMRahmaniBMohamedZet al

(2014) 9:e108693
