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Methods We conducted a systematic review of studies from PubMed, Embase, and Cochrane databases (until November 2024), as well as relevant abstracts from Digestive Disease Week (DDW) 2024 and American College of Gastroenterology (ACG) 2024 to assess the impact of GLP-1 receptor agonists (GLP-1 RAs) on EGD

GLP-1 receptor agonists can reduce thirst signals and increase fluid loss through gastrointestinal changes, making intentional hydration critical during treatment