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Winfrey first revealed that she was using a type of GLP-1 medication in December 2023, but didn't disclose which one

Or dealing with unpredictable gut issues while miles from a convenient pit stop

HOLST: Yeah, so the way I would like to put it is there are two major areas of effects of GLP-1 that we really haven't talked about, and one is the vascular system

"Once-Weekly Semaglutide in Adults with Overweight or Obesity." New England Journal of Medicine , 2021

Effect of oral semaglutide on the pharmacokinetics of lisinopril, warfarin, digoxin, and metformin in healthy subjects