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But the biological plausibility is sound, and some clinicians are incorporating this strategy into their long-term GLP-1 treatment plans
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How long does it take to see results from combination therapy

Continue with the lifestyle habits mentioned above, such as getting adequate fiber, hydration, and movement
Therefore, given the potential for increased risk of fat mass gain, persistent muscle loss, and declining physical capacity with weight cycling, coupled with evidence that the prevalence of sarcopenic obesity is estimated to be 20% in obese treatment-seeking adults [15], it is possible voluntary weight loss followed by involuntary regain may increase (or further exacerbate) the risk of sarcopenia and sarcopenic obesity, particularly in older adults

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