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The Phase 3 ATTAIN-1 trial had good results that led to this approval, but not all positive: 12.4% average weight loss (27.3 lbs) at highest dose Lower than the 15-20% weight loss seen with injectables Wegovy and Zepbound Nearly 1/4 of participants on the highest dose reported vomiting Vomiting rates are much higher than injectable GLP-1s However, there is likely a niche for Foundayo (along with the pill version of Wegovy) due to convenience: No refrigeration requirements or injection site reactions Eliminates barriers for patients avoiding injectables due to stigma, needle aversion, or storage constraints It's possible we could see this as a "maintenance" therapy after an initial injectable course

While GLP-1 weight loss peptides such as semaglutide and tirzepatide have become buzzworthy for th...

| Walgreens is wading into the self-pay GLP-1 space, going head-to-head with telehealth subscription offerings.

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are emerging as potential neuroprotective drugs in neurodegenerative diseases

GLP-1R Agonist Evolution: From Diabetes to Weight Loss | Peptidic GLP-1R agonists have received significant media coverage over the past year for their astounding efficacy in several indications