glp 1 agonist uses glp-1_analogs [TUSOM The current significance and prospects
Description
On April 1, 2026, the FDA approved Eli Lillys FOUNDAYO (orforglipron) , the second oral GLP-1 approved for obesity, and arguably the one with the more patient-friendly convenience profile

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Samms RJ, Kusminski CM

The development of GLP-/GIP dual agonists provides a more complete scheme for the treatment of metabolic diseases, but the safety of more dual agonists or multiple agonists in clinical trials is also worthy of attention

aHR, adjusted hazard ratio

In the SURMOUNT-1 trials, the tirzepatide group lost about 20.2% of baseline body weight in 72 weeks, while the semaglutide group lost about 13.7 %
