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Gde P, Lund-Andersen H, Parving H-H, Pedersen O (2008) Effect of a multifactorial intervention on mortality in type 2 diabetes

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Activated macrophages release large amounts of inflammatory mediators such as IL-1, IL-6, IL-8, TNF-, ROS and chemokines, leukotrienes and prostaglandins, matrix metalloproteinases (MMP), etc