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Description
STEP 9 was a knee-specific trial

The proportion of lean to total weight loss was comparable to other obesity treatments

In patients with decompensated heart failure, begin dosing when patients are hemodynamically stable


Zepbound was approved by the FDA in November for chronic weight management in adults with obesity or overweight with at least one weight-related condition, such as high cholesterol, high blood pressure, or type 2 diabetes

In the central nervous system, it acts on appetite-regulating centers to reduce hunger and food intake, contributing to weight loss
