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doi: 10.1093/ajhp/zxz179 [DOI] [PubMed] [Google Scholar] 65

Safety Profile The safety profile of orforglipron across its Phase 2 and Phase 3 clinical development program has been consistent with the established safety characteristics of the GLP-1 receptor agonist class

Kulcsar K, Coleman C, Beck S, Frieman M

Patients should seek help immediately about any side effects that are severe or do not go away

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many patients stop due to side effects , supply , or coverage issues