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Beyond their metabolic effects, GLP-1 RAs have demonstrated cardiovascular and renal benefits in large outcome trials, including reductions in major adverse cardiovascular events (MACE) and attenuation of albuminuria progression ( Table 1 , renal eligibility criteria across landmark GLP-1 RA cardiovascular and kidney outcome trials consistently excluded dialysis-dependent patients, resulting in a persistent lack of randomized evidence in this high-risk population

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For panic disorder, post-traumatic stress disorder (PTSD), and social anxiety disorder, the initial dose may be lower, often starting at 25 mg per day to minimize the risk of increased anxiety at the beginning of treatment

Eligibility for liraglutide for weight loss is: Body Mass Index BMI 30 or higher or 27 or higher with weight related condition

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