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This narrative review discusses the justification for focus on lean mass preservation and reviews the status of relevant drugs in development.

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Recent evidence from the STEP-HFpEF and STEP-HFpEF-DM trials provides the first robust data supporting the efficacy of GLP-1 RAs, specifically semaglutide, in improving the quality of life in obese patients with HFpEF

You may be a good candidate for Semaglutide injections if: Your BMI is 30 or higher, or 27+ with weight-related health conditions