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Olubunmi Oladunjoye discusses GLP-1 medications for weight management, including their rise in popularity and possible side effects.

In this piece, I share why most GLP-1 contracts reward the wrong outcome, the three commercial models that dominate this market, and where each one has an opportunity to improve, and how Twin built a commercial model that finally puts the vendor's incentives on the same side as yours.

Lancet Gastroenterol Hepatol

However, as DPP4 recognizes other substrates such as chemokines, growth factors and neuropeptides, pleiotropic effects have been observed in patients treated with DPP4i

When activated, these receptors appear to dampen the dopamine-driven reward response that makes alcohol feel pleasurable and reinforcing effectively quieting the neurological "pull" toward drinking

Promotes healthy weight management