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Although rare, colonoscopies like all procedures have some risks

Alternate between left and right side of the abdomen each week

faces higher GLP-1 drug prices due to market forces including research and development expenses, patent protections, demand outpacing supply and limited government regulation on drug pricing

Innovative designs incorporating active comparators, adaptive frameworks, and biomarker-driven endpoints (e.g., CSF/serum NfL, p-tau, microglial PET, synaptic markers) will be critical to generate interpretable efficacy signals