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Veterans Affairs (VA) analysis published in JAMA Ophthalmology , semaglutide use was associated with approximately double the risk of nonarteritic anterior ischemic optic neuropathy (NAION) compared with SGLT2 inhibitors in patients with type 2 diabetes. The study followed more than 102,000 patients for up to seven years, making it the most comprehensive assessment so far of this potential association
About the ESSENCE trial Part 1 of the ESSENCE trial evaluated the effect of once-weekly semaglutide 2.4 mg on liver tissue (histology) compared to placebo on top of standard of care for the first 800 randomised people at 72 weeks
From Injection to Complexion GLP-1 (glucagon-like peptide-1) drugs have become a major force in both metabolic health and weight loss

It is important to distinguish dysgeusia from other oral symptoms such as dry mouth (xerostomia) or oral infections, which may also occur during treatment

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If you get nausea and headaches from blood thinners, and you get nausea and headaches from semaglutide, these two effects can double up and make your time somewhat miserable each time you take a dose
