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Overall, these findings might suggest that the metabolic benefits of liraglutide, at least in the short term, may occur independently of detectable changes in gut microbial diversity or composition

It promotes lean mass development while encouraging fat breakdown as a secondary effect

Rena, G., Hardie, D

Gastrointestinal Tolerance and Dose Adjustment Strategies Nausea, vomiting, and constipation are common early-phase side effects that often improve with time or dietary modification

GLP-1 receptor agonists are MHRA-licensed prescription medicines with extensive clinical trial evidence for type 2 diabetes and obesity management

Due to the above-mentioned effects of TZD on glycemic, hepatic metabolism, and inflammation, treatment with dual-agonism may reduce or reverse liver damage (lobular inflammation, hepatic steatosis, liver cell damage, and fibrosis) and metabolic dysfunction (35, 41)