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However, because GLP-1s can produce rapid weight loss (12 lbs/week), the absolute amount of lean mass lost can be significant

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c The alternative approach they examined was behavioral interventions, nutritional support and a lower-cost medication regimen

Semaglutide is typically administered as a weekly injection, and this schedule is crucial for maintaining consistent results

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"Taking GLP-1s may be one of those decisions people need to discuss with their doctor, knowing that it requires a long-term commitment and may not be the best fit for those who struggle with taking medication daily or weekly." Copyright 2026 Nexstar Media, Inc