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Description
Putting orforglipron in context Because obesity therapies are evolving rapidly in a market dominated by injectables since semaglutides weight-loss approval in 2021, it is helpful to view orforglipron alongside established and emerging incretin-based drugs

doi: 10.1016/j.jacc.2020.09.590

J Clin Endocrinol Metab (2020) 105(8):e2695709

These GLP-1 agonists have skyrocketed in popularity

With the right approach, you can mitigate many of these potential long-term risks

Although activation of the GLP-1 receptor primarily facilitates weight reduction through appetite suppression, the inclusion of GIP receptor agonism offers supplementary and synergistic advantages, including improved insulin sensitivity and overall metabolic health
